What precautionary measures should be preferred for treatment of drug overdose?

A teenage patient was admitted in emergency room because of overdose of medicine. He was taking Paracetamol, Tylenol and sleeping pill. What precautionary measures should be preferred for treatment of drug overdose?

i will upload an example because i want to take clinical decision regarding to the case using Evidence based medicine using PICOS MODEL

P:Patient, Population, or Problem

I:INTERVENTION

C:COMPARISION

O:OUTCOME

S:SETTING

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